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SOLVED: 70. The conversion of glutamate to glutamine is unfavorable. In order for this transformation to occur in the cell, it must be coupled to the hydrolysis of ATP. Consider two possible

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Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations - ScienceDirect

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The impact of manganese overexposure on glutamate-glutamine cycle.

Glutamate is an essential mediator in glutamine‐amplified insulin secretion - Han - 2021 - Journal of Diabetes Investigation - Wiley Online Library